Publications
Selected publications from the Rappel Lab.
2025
Spiral defect chaos with intermittency increases mean termination time
Mulimani, Mahesh Kumar, Rappel, Wouter-Jan
Single-cell chiral symmetry breaking under confinement
Echeverria-Alar, Sebastian, Narasimhan, Badri Narayanan, Fraley, Stephanie I, Rappel, Wouter-Jan
Prediction of excitable wave dynamics using machine learning
Mulimani, Mahesh Kumar, Echeverria-Alar, Sebastian, Reiss, Michael, Rappel, Wouter-Jan
Perspective on interdisciplinary approaches on chemotaxis
Simmchen, Juliane, Gordon, Daniel, MacKenzie, John, Pagonabarraga, Ignacio, Roggatz, Christina C, Endres, Robert G, Xiao, Zuyao, Friedrich, Benjamin M, Qiu, Tian, Painter, Kevin J
Particle model of creation and annihilation captures termination dynamics of spiral defect chaos
Tyree, Timothy J, Reiss, Michael, Rappel, Wouter-Jan
Global versus local matrix remodeling drives rotational versus invasive collective migration of epithelial cells
Ranamukhaarachchi, Sural K, Walker, Alyssa, Tang, Man-Ho, Leineweber, William D, Lam, Sophia, Rappel, Wouter-Jan, Fraley, Stephanie I
Coupling Step-Wise Motility and Traction Force Patterns in chemotaxing cells
Echeverría-Alar, Sebastián, Rappel, Wouter-Jan
Boundary-driven delayed-feedback control of spatiotemporal dynamics in excitable media
Echeverría-Alar, Sebastián, Rappel, Wouter-Jan
2024
Spatially Conserved Spiral Wave Activity During Human Atrial Fibrillation
Rappel, Wouter-Jan, Baykaner, Tina, Zaman, Junaid, Ganesan, Prasanth, Rogers, Albert J, Narayan, Sanjiv M
Eukaryotic chemotaxis under periodic stimulation shows temporal gradient dependence
Karmakar, Richa, Karanam, Aravind, Tang, Man-Ho, Rappel, Wouter-Jan
Coupled Dynamics in Phenotype and Tissue Spaces Shape the Three-Dimensional Cancer Invasion
Naylor, Austin, Libmann, Maximilian, Raab, Izabel, Rappel, Wouter-Jan, Sun, Bo
Annihilation dynamics during spiral defect chaos revealed by particle models
Tyree, Timothy J, Murphy, Patrick, Rappel, Wouter-Jan
2023
The Molecular Basis for Cell Migration in 3D
Martin, NR, Tang, M-H, Rappel, W-J, Weiner, OD
A role for ethylene signaling and biosynthesis in regulating and accelerating CO2‐and abscisic acid‐mediated stomatal movements in Arabidopsis
Azoulay‐Shemer, Tamar, Schulze, Sebastian, Nissan‐Roda, Dikla, Bosmans, Krystal, Shapira, Or, Weckwerth, Philipp, Zamora, Olena, Yarmolinsky, Dmitry, Trainin, Taly, Kollist, Hannes
2022
Stochastic termination of spiral wave dynamics in cardiac tissue
Rappel, Wouter-Jan, Krummen, David E, Baykaner, Tina, Zaman, Junaid, Donsky, Alan, Swarup, Vijay, Miller, John M, Narayan, Sanjiv M
Predicting acute termination and non-termination during ablation of human atrial fibrillation using quantitative indices
Kappel, Cole, Reiss, Michael, Rodrigo, Miguel, Ganesan, Prasanth, Narayan, Sanjiv M, Rappel, Wouter-Jan
Intermittent trapping of spiral waves in a cardiac model
Rappel, Wouter-Jan
Boolean modelling in plant biology
Karanam, Aravind, Rappel, Wouter-Jan
2021
Three dimensional reconstruction to visualize atrial fibrillation activation patterns on curved atrial geometry
Abad, Ricardo, Collart, Orvil, Ganesan, Prasanth, Rogers, AJ, Alhusseini, Mahmood I, Rodrigo, Miguel, Narayan, Sanjiv M, Rappel, Wouter-Jan
The mechanics and dynamics of cancer cells sensing noisy 3D contact guidance
Kim, Jihan, Cao, Yuansheng, Eddy, Christopher, Deng, Youyuan, Levine, Herbert, Rappel, Wouter-Jan, Sun, Bo
System and method to determine driving sources of heart rhythm disorders
Rappel, Wouter-Jan, Vidmar, David
Machine learned cellular phenotypes in cardiomyopathy predict sudden death
Rogers, Albert J, Selvalingam, Anojan, Alhusseini, Mahmood I, Krummen, David E, Corrado, Cesare, Abuzaid, Firas, Baykaner, Tina, Meyer, Christian, Clopton, Paul, Giles, Wayne
Electrical substrate ablation for refractory ventricular fibrillation: results of the AVATAR study
Krummen, David E, Ho, Gordon, Hoffmayer, Kurt S, Schweis, Franz N, Baykaner, Tina, Rogers, AJ, Han, Frederick T, Hsu, Jonathan C, Viswanathan, Mohan N, Wang, Paul J
Deep dive into CO2-dependent molecular mechanisms driving stomatal responses in plants
Dubeaux, Guillaume, Hsu, Po-Kai, Ceciliato, Paulo HO, Swink, Kelsey J, Rappel, Wouter-Jan, Schroeder, Julian I
Coupling traction force patterns and actomyosin wave dynamics reveals mechanics of cell motion
Ghabache, Elisabeth, Cao, Yuansheng, Miao, Yuchuan, Groisman, Alex, Devreotes, Peter N, Rappel, Wouter‐Jan
Cellular memory in eukaryotic chemotaxis depends on the background chemoattractant concentration
Karmakar, Richa, Tang, Man-Ho, Yue, Haicen, Lombardo, Daniel, Karanam, Aravind, Camley, Brian A, Groisman, Alex, Rappel, Wouter-Jan
Cell dispersal by localized degradation of a chemoattractant
Karmakar, Richa, Tyree, Timothy, Gomer, Richard H, Rappel, Wouter-Jan
Boolink: a graphical interface for open access Boolean network simulations and use in guard cell CO2 signaling
Karanam, Aravind, He, David, Hsu, Po-Kai, Schulze, Sebastian, Dubeaux, Guillaume, Karmakar, Richa, Schroeder, Julian I, Rappel, Wouter-Jan
2020
Tissue topography steers migrating Drosophila border cells
Dai, Wei, Guo, Xiaoran, Cao, Yuansheng, Mondo, James A, Campanale, Joseph P, Montell, Brandon J, Burrous, Haley, Streichan, Sebastian, Gov, Nir, Rappel, Wouter-Jan
Termination of persistent atrial fibrillation by ablating sites that control large atrial areas
Bhatia, Neal K, Rogers, Albert J, Krummen, David E, Hossainy, Samir, Sauer, William, Miller, John M, Alhusseini, Mahmood I, Peszek, Adam, Armenia, Erin, Baykaner, Tina
Novel micropatterning technique reveals dependence of cell-substrate adhesion and migration of social amoebas on parental strain, development, and fluorescent markers
Karmakar, Richa, Schich, Christoph, Kamprad, Nadine, Scheller, Vanessa, Gutierrez, Edgar, Groisman, Alex, Rappel, Wouter-Jan, Tarantola, Marco
Machine learning to classify intracardiac electrical patterns during atrial fibrillation: machine learning of atrial fibrillation
Alhusseini, Mahmood I, Abuzaid, Firas, Rogers, Albert J, Zaman, Junaid AB, Baykaner, Tina, Clopton, Paul, Bailis, Peter, Zaharia, Matei, Wang, Paul J, Rappel, Wouter-Jan
Machine learned cellular phenotypes predict outcome in ischemic cardiomyopathy
Rogers, Albert J, Selvalingam, Anojan, Alhusseini, Mahmood I, Krummen, David E, Corrado, Cesare, Abuzaid, Firas, Baykaner, Tina, Meyer, Christian, Clopton, Paul, Giles, Wayne
Flower-like patterns in multi-species bacterial colonies
Xiong, Liyang, Cao, Yuansheng, Cooper, Robert, Rappel, Wouter-Jan, Hasty, Jeff, Tsimring, Lev
2019
Wavefront field mapping reveals a physiologic network between drivers where ablation terminates atrial fibrillation
Leef, George, Shenasa, Fatemah, Bhatia, Neal K, Rogers, Albert J, Sauer, William, Miller, John M, Swerdlow, Mark, Tamboli, Mallika, Alhusseini, Mahmood I, Armenia, Erin
Rotor Mapping in Patients with Atrial Fibrillation
Narayan, Sanjiv M, Baykaner, Tina, Brodt, Chad, Zaman, Junaid AB, Kowalewski, Christopher AB, Vidmar, David, Rappel, Wouter‐Jan
Response by Bhatia et al to Letter Regarding Article,“Wavefront Field Mapping Reveals a Physiologic Network Between Drivers Where Ablation Terminates Atrial Fibrillation”
Bhatia, Neal K, Rappel, Wouter-Jan, Narayan, Sanjiv M
Plasticity of cell migration resulting from mechanochemical coupling
Cao, Yuansheng, Ghabache, Elisabeth, Rappel, Wouter-Jan
Mapping Atrial Organized Areas Rather than Phase Singularities in Atrial Fibrillation
Bhatia, Neal K, Rappel, Wouter-Jan, Narayan, Sanjiv M
Extinction dynamics of spiral defect chaos
Vidmar, David, Rappel, Wouter-Jan
Contact Mapping and Ablation of Complex Cardiac Arrhythmias
Narayan, Sanjiv M, Zaman, Junaid AB, Brodt, Chad, Shenasa, Fatemah, Baykaner, Tina, Rappel, Wouter‐Jan
Chaotic tip trajectories of a single spiral wave in the presence of heterogeneities
Lombardo, Daniel M, Rappel, Wouter-Jan
Cell motility dependence on adhesive wetting
Cao, Yuansheng, Karmakar, Richa, Ghabache, Elisabeth, Gutierrez, Edgar, Zhao, Yanxiang, Groisman, Alex, Levine, Herbert, Camley, Brian A, Rappel, Wouter-Jan
A minimal computational model for three-dimensional cell migration
Cao, Yuansheng, Ghabache, Elisabeth, Miao, Yuchuan, Niman, Cassandra, Hakozaki, Hiroyuki, Reck-Peterson, Samara L, Devreotes, Peter N, Rappel, Wouter-Jan
2018
To the Editor—On the deformation and interpolation of phase maps
Vidmar, David, Rappel, Wouter-Jan
The cAMP-induced G protein subunits dissociation monitored in live Dictyostelium cells by BRET reveals two activation rates, a positive effect of caffeine and potential role of microtubules
Islam, AFM Tariqul, Yue, Haicen, Scavello, Margarethakay, Haldeman, Pearce, Rappel, Wouter-Jan, Charest, Pascale G
Successful ventricular fibrillation functional substrate ablation via a single vascular access site
Ho, Gordon, Hoffmayer, Kurt S, Villongco, Christopher T, Vidmar, David, Rappel, Wouter-Jan, Krummen, David E
Possible impacts of rising CO2 on crop water use efficiency and food security
Scavo, Alexander J, Sidhom, Morgana, Rangel, Felipe J, Miaule, Alexandre, Emuka, Christine, Poomchongko, Nusra, Ali, Suwayda, Rappel, Wouter-Jan, Schroeder, Julian I
Minimal network topologies for signal processing during collective cell chemotaxis
Yue, Haicen, Camley, Brian A, Rappel, Wouter-Jan
Insights into the molecular mechanisms of CO2-mediated regulation of stomatal movements
Zhang, Jingbo, De-oliveira-Ceciliato, Paulo, Takahashi, Yohei, Schulze, Sebastian, Dubeaux, Guillaume, Hauser, Felix, Azoulay-Shemer, Tamar, Toldsepp, Kadri, Kollist, Hannes, Rappel, Wouter-Jan
Identification of SLAC1 anion channel residues required for CO2/bicarbonate sensing and regulation of stomatal movements
Zhang, Jingbo, Wang, Nuo, Miao, Yinglong, Hauser, Felix, McCammon, J Andrew, Rappel, Wouter-Jan, Schroeder, Julian I
Identification and characterization of sites where persistent atrial fibrillation is terminated by localized ablation
Zaman, Junaid AB, Sauer, William H, Alhusseini, Mahmood I, Baykaner, Tina, Borne, Ryan T, Kowalewski, Christopher AB, Busch, Sonia, Zei, Paul C, Park, Shirley, Viswanathan, Mohan N
Characterizing electrogram signal fidelity and the effects of signal contamination on mapping human persistent atrial fibrillation
Vidmar, David, Alhusseini, Mahmood I, Narayan, Sanjiv M, Rappel, Wouter-Jan
Adaptation in living systems
Tu, Yuhai, Rappel, Wouter-Jan
2017
Two independent mapping techniques identify rotational activity patterns at sites of local termination during persistent atrial fibrillation
Alhusseini, Mahmood, Vidmar, David, Meckler, Gabriela L, Kowalewski, Christopher A, Shenasa, Fatemah, Wang, Paul J, Narayan, Sanjiv M, RAPPEL, WOUTER‐JAN
Systematic reduction of a detailed atrial myocyte model
Lombardo, Daniel M, Rappel, Wouter-Jan
Spatiotemporal progression of early human ventricular fibrillation
Vidmar, David, Krummen, David E, Hayase, Justin, Narayan, Sanjiv M, Ho, Gordon, Rappel, Wouter-Jan
Rotors exhibit greater surface ECG variation during ventricular fibrillation than focal sources due to wavebreak, secondary rotors, and meander
Ho, Gordon, Villongco, Christopher T, Yousefian, Omid, Bradshaw, Aaron, Nguyen, Andrew, Faiwiszewski, Yonatan, Hayase, Justin, Rappel, Wouter‐Jan, McCulloch, Andrew D, Krummen, David E
Physical models of collective cell motility: from cell to tissue
Camley, Brian A, Rappel, Wouter-Jan
Mechanisms of cell polarization
Rappel, Wouter-Jan, Edelstein-Keshet, Leah
Inferring single-cell behaviour from large-scale epithelial sheet migration patterns
Lee, Rachel M, Yue, Haicen, Rappel, Wouter-Jan, Losert, Wolfgang
Crawling and turning in a minimal reaction-diffusion cell motility model: Coupling cell shape and biochemistry
Camley, Brian A, Zhao, Yanxiang, Li, Bo, Levine, Herbert, Rappel, Wouter-Jan
Cell-to-cell variation sets a tissue-rheology–dependent bound on collective gradient sensing
Camley, Brian A, Rappel, Wouter-Jan
2016
Reconstitution of CO2 regulation of SLAC1 anion channel and function of CO2-permeable PIP2; 1 aquaporin as CARBONIC ANHYDRASE4 interactor
Wang, Cun, Hu, Honghong, Qin, Xue, Zeise, Brian, Xu, Danyun, Rappel, Wouter-Jan, Boron, Walter F, Schroeder, Julian I
Modeling contact inhibition of locomotion of colliding cells migrating on micropatterned substrates
Kulawiak, Dirk Alexander, Camley, Brian A, Rappel, Wouter-Jan
Excitable waves and direction-sensing in Dictyostelium discoideum: steps towards a chemotaxis model
Bhowmik, Arpan, Rappel, Wouter-Jan, Levine, Herbert
Determining conduction patterns on a sparse electrode grid: Implications for the analysis of clinical arrhythmias
Vidmar, David, Narayan, Sanjiv M, Krummen, David E, Rappel, Wouter-Jan
Contact inhibition of locomotion determines cell–cell and cell–substrate forces in tissues
Zimmermann, Juliane, Camley, Brian A, Rappel, Wouter-Jan, Levine, Herbert
Comparison of detailed and simplified models of human atrial myocytes to recapitulate patient specific properties
Lombardo, Daniel M, Fenton, Flavio H, Narayan, Sanjiv M, Rappel, Wouter-Jan
Collective signal processing in cluster chemotaxis: Roles of adaptation, amplification, and co-attraction in collective guidance
Camley, Brian A, Zimmermann, Juliane, Levine, Herbert, Rappel, Wouter-Jan
CO2 sensing and CO2 regulation of stomatal conductance: advances and open questions
Engineer, Cawas B, Hashimoto-Sugimoto, Mimi, Negi, Juntaro, Israelsson-Nordström, Maria, Azoulay-Shemer, Tamar, Rappel, Wouter-Jan, Iba, Koh, Schroeder, Julian I
Cell–cell communication during collective migration
Rappel, Wouter-Jan
2015
Phase synchrony reveals organization in human atrial fibrillation
Vidmar, David, Narayan, Sanjiv M, Rappel, Wouter-Jan
Modifying ventricular fibrillation by targeted rotor substrate ablation: proof‐of‐concept from experimental studies to clinical VF
Krummen, David E, Hayase, Justin, Vampola, Stephen P, Ho, Gordon, Schricker, Amir A, Lalani, Gautam G, Baykaner, Tina, Coe, Taylor M, Clopton, Paul, RAPPEL, WOUTER‐JAN
Mechanisms for the termination of atrial fibrillation by localized ablation: computational and clinical studies
Rappel, Wouter-Jan, Zaman, Junaid AB, Narayan, Sanjiv M
Distinct cellular locations of carbonic anhydrases mediate carbon dioxide control of stomatal movements
Hu, Honghong, Rappel, Wouter-Jan, Occhipinti, Rossana, Ries, Amber, Böhmer, Maik, You, Lei, Xiao, Chuanlei, Engineer, Cawas B, Boron, Walter F, Schroeder, Julian I
2014
Velocity alignment leads to high persistence in confined cells
Camley, Brian A, Rappel, Wouter-Jan
Rotors in Human Atrial Fibrillation
Narayan, Sanjiv M, Rappel, Wouter-Jan
Rotor stability separates sustained ventricular fibrillation from self-terminating episodes in humans
Krummen, David E, Hayase, Justin, Morris, David J, Ho, Jeffrey, Smetak, Miriam R, Clopton, Paul, Rappel, Wouter-Jan, Narayan, Sanjiv M
Polarity mechanisms such as contact inhibition of locomotion regulate persistent rotational motion of mammalian cells on micropatterns
Camley, Brian A, Zhang, Yunsong, Zhao, Yanxiang, Li, Bo, Ben-Jacob, Eshel, Levine, Herbert, Rappel, Wouter-Jan
Modeling self-organized spatio-temporal patterns of PIP3 and PTEN during spontaneous cell polarization
Knoch, Fabian, Tarantola, Marco, Bodenschatz, Eberhard, Rappel, Wouter-Jan
Intercellular stress reconstitution from traction force data
Zimmermann, Juliane, Hayes, Ryan L, Basan, Markus, Onuchic, José N, Rappel, Wouter-Jan, Levine, Herbert
Human atrial fibrillation initiates via organized rather than disorganized mechanisms
Schricker, Amir A, Lalani, Gautam G, Krummen, David E, Rappel, Wouter-Jan, Narayan, Sanjiv M
How input noise limits biochemical sensing in ultrasensitive systems
Hu, Bo, Rappel, Wouter-Jan, Levine, Herbert
Cellular memory in eukaryotic chemotaxis
Skoge, Monica, Yue, Haicen, Erickstad, Michael, Bae, Albert, Levine, Herbert, Groisman, Alex, Loomis, William F, Rappel, Wouter-Jan
Cell substratum adhesion during early development of Dictyostelium discoideum
Tarantola, Marco, Bae, Albert, Fuller, Danny, Bodenschatz, Eberhard, Rappel, Wouter-Jan, Loomis, William F
2013
Theoretical considerations for mapping activation in human cardiac fibrillation
Rappel, Wouter-Jan, Narayan, Sanjiv M
The physics of eukaryotic chemotaxis
Levine, Herbert, Rappel, Wouter-Jan
Periodic migration in a physical model of cells on micropatterns
Camley, Brian A, Zhao, Yanxiang, Li, Bo, Levine, Herbert, Rappel, Wouter-Jan
Panoramic electrophysiological mapping but not electrogram morphology identifies stable sources for human atrial fibrillation: stable atrial fibrillation rotors and focal sources relate poorly to fractionated electrograms
Narayan, Sanjiv M, Shivkumar, Kalyanam, Krummen, David E, Miller, John M, Rappel, Wouter-Jan
Alignment of cellular motility forces with tissue flow as a mechanism for efficient wound healing
Basan, Markus, Elgeti, Jens, Hannezo, Edouard, Rappel, Wouter-Jan, Levine, Herbert
A three-dimensional finite element model of human atrial anatomy: New methods for cubic Hermite meshes with extraordinary vertices
Gonzales, Matthew J, Sturgeon, Gregory, Krishnamurthy, Adarsh, Hake, Johan, Jonas, René, Stark, Paul, Rappel, Wouter-Jan, Narayan, Sanjiv M, Zhang, Yongjie, Segars, W Paul
2012
Treatment of atrial fibrillation by the ablation of localized sources: CONFIRM (Conventional Ablation for Atrial Fibrillation With or Without Focal Impulse and Rotor Modulation) trial
Narayan, Sanjiv M, Krummen, David E, Shivkumar, Kalyanam, Clopton, Paul, Rappel, Wouter-Jan, Miller, John M
Swirls, fingers and directed bulk motility in spreading epithelial sheets
Basan, Markus, Elgeti, Jens, Hannezo, Edouard, Rappel, Wouter-Jan, Levine, Herbert
Noise effects in nonlinear biochemical signaling
Bostani, Neda, Kessler, David A, Shnerb, Nadav M, Rappel, Wouter-Jan, Levine, Herbert
Innate non-specific cell substratum adhesion
Loomis, William F, Fuller, Danny, Gutierrez, Edgar, Groisman, Alex, Rappel, Wouter-Jan
Incoherent feedforward control governs adaptation of activated ras in a eukaryotic chemotaxis pathway
Takeda, Kosuke, Shao, Danying, Adler, Micha, Charest, Pascale G, Loomis, William F, Levine, Herbert, Groisman, Alex, Rappel, Wouter-Jan, Firtel, Richard A
How input fluctuations reshape the dynamics of a biological switching system
Hu, Bo, Kessler, David A, Rappel, Wouter-Jan, Levine, Herbert
Coupling actin flow, adhesion, and morphology in a computational cell motility model
Shao, Danying, Levine, Herbert, Rappel, Wouter-Jan
Computational mapping identifies localized mechanisms for ablation of atrial fibrillation
Narayan, Sanjiv M, Krummen, David E, Enyeart, Michael W, Rappel, Wouter-Jan
Clinical mapping approach to diagnose electrical rotors and focal impulse sources for human atrial fibrillation
Narayan, Sanjiv M, Krummen, David E, RAPPEL, WOUTER‐JAN
Adaptation in a eukaryotic pathway: combining experiments with modeling
Rappel, Wouter-Jan, Firtel, Richard
Modelling self-propelled deformable cell motion in the Dictyostelium mound: a status report
Rappel, Wouter-Jan, Levine, Herbert, Nicol, Alastair, Loomis, William F
2011
“Self-assisted” amoeboid navigation in complex environments
Hecht, Inbal, Levine, Herbert, Rappel, Wouter-Jan, Ben-Jacob, Eshel
Quantifying information transmission in eukaryotic gradient sensing and chemotactic response
Hu, Bo, Chen, Wen, Levine, Herbert, Rappel, Wouter-Jan
How geometry and internal bias affect the accuracy of eukaryotic gradient sensing
Hu, Bo, Chen, Wen, Rappel, Wouter-Jan, Levine, Herbert
Effects of input noise on a simple biochemical switch
Hu, Bo, Kessler, David A, Rappel, Wouter-Jan, Levine, Herbert
Design principles and specificity in biological networks with cross activation
Hu, Bo, Levine, Herbert, Rappel, Wouter-Jan
Activated membrane patches guide chemotactic cell motility
Hecht, Inbal, Skoge, Monica L, Charest, Pascale G, Ben-Jacob, Eshel, Firtel, Richard A, Loomis, William F, Levine, Herbert, Rappel, Wouter-Jan
2010
The role of cell contraction and adhesion in dictyostelium motility
Buenemann, Mathias, Levine, Herbert, Rappel, Wouter-Jan, Sander, Leonard M
Physical limits on cellular sensing of spatial gradients
Hu, Bo, Chen, Wen, Rappel, Wouter-Jan, Levine, Herbert
Phenomenological approach to eukaryotic chemotactic efficiency
Hu, Bo, Fuller, Danny, Loomis, William F, Levine, Herbert, Rappel, Wouter-Jan
Gradient sensing in defined chemotactic fields
Skoge, Monica, Adler, Micha, Groisman, Alex, Levine, Herbert, Loomis, William F, Rappel, Wouter-Jan
External and internal constraints on eukaryotic chemotaxis
Fuller, Danny, Chen, Wen, Adler, Micha, Groisman, Alex, Levine, Herbert, Rappel, Wouter-Jan, Loomis, William F
Eukaryotic chemotaxis and its limitations due to stochastic sensing
Levine, Herbert, Loomis, William F, Rappel, Wouter-Jan
Computational model for cell morphodynamics
Shao, Danying, Rappel, Wouter-Jan, Levine, Herbert
A comparison of deterministic and stochastic simulations of neuronal vesicle release models
Modchang, Charin, Nadkarni, Suhita, Bartol, Thomas M, Triampo, Wannapong, Sejnowski, Terrence J, Levine, Herbert, Rappel, Wouter-Jan
2009
The role of receptor occupancy noise in eukaryotic chemotaxis
Rappel, Wouter-Jan, Levine, Herbert
Mechanisms and constraints on yeast MAPK signaling specificity
Hu, Bo, Rappel, Wouter-Jan, Levine, Herbert
Eukaryotic chemotaxis
Rappel, Wouter‐Jan, Loomis, William F
Determining the scale of the Bicoid morphogen gradient
Hecht, Inbal, Rappel, Wouter-Jan, Levine, Herbert
Compartmentalization of second messengers in neurons: a mathematical analysis
Chen, Wen, Levine, Herbert, Rappel, Wouter-Jan
2008
Repolarization and activation restitution near human pulmonary veins and atrial fibrillation initiation: a mechanism for the initiation of atrial fibrillation by premature beats
Narayan, Sanjiv M, Kazi, Dhruv, Krummen, David E, Rappel, Wouter-Jan
Receptor noise limitations on chemotactic sensing
Rappel, Wouter-Jan, Levine, Herbert
Receptor noise and directional sensing in eukaryotic chemotaxis
Rappel, Wouter-Jan, Levine, Herbert
Directed Motility and Dictyostelium Aggregation
Levine, Herbert, Rappel, Wouter-Jan
A mathematical analysis of second messenger compartmentalization
Chen, Wen, Levine, Herbert, Rappel, Wouter-Jan
2007
Quantifying noise levels of intercellular signals
Wang, Kai, Rappel, Wouter-Jan, Kerr, Rex, Levine, Herbert
Flow photolysis for spatiotemporal stimulation of single cells
Beta, Carsten, Wyatt, Danica, Rappel, Wouter-Jan, Bodenschatz, Eberhard
2006
Swarming patterns in microorganisms: Some new modeling results
Levine, Herbert, Ben-Jacob, Eshel, Cohen, Inon, Rappel, Wouter-Jan
Embryonic pattern scaling achieved by oppositely directed morphogen gradients
McHale, Peter, Rappel, Wouter-Jan, Levine, Herbert
Division accuracy in a stochastic model of Min oscillations in Escherichia coli
Kerr, Rex A, Levine, Herbert, Sejnowski, Terrence J, Rappel, Wouter-Jan
Directional sensing in eukaryotic chemotaxis: a balanced inactivation model
Levine, Herbert, Kessler, David A, Rappel, Wouter-Jan
Dictyostelium discoideum chemotaxis: threshold for directed motion
Song, Loling, Nadkarni, Sharvari M, Bödeker, Hendrik U, Beta, Carsten, Bae, Albert, Franck, Carl, Rappel, Wouter-Jan, Loomis, William F, Bodenschatz, Eberhard
Coupling-induced cooperative behaviour in dynamic ferromagnetic cores in the presence of a noise floor
Bulsara, Adi R, Lindner, John F, In, Visarath, Kho, Andy, Baglio, Salvatore, Sacco, Vincenzo, Ando, Bruno, Longhini, Patrick, Palacios, Antonio, Rappel, Wouter-Jan
2005
Modeling wave propagation in realistic heart geometries using the phase-field method
Fenton, Flavio H, Cherry, Elizabeth M, Karma, Alain, Rappel, Wouter-Jan
Membrane-bound Turing patterns
Levine, Herbert, Rappel, Wouter-Jan
Excitation-contraction coupling gain and cooperativity of the cardiac ryanodine receptor: a modeling approach
Wang, Kai, Tu, Yuhai, Rappel, Wouter-Jan, Levine, Herbert
Dynamics of conduction blocks in a model of paced cardiac tissue
Henry, Hervé, Rappel, Wouter-Jan
Coupling‐Induced Oscillations In Overdamped Bistable Systems In The Presence Of A Noise Floor
Bulsara, AR, In, V, Kho, A, Lindner, J, Rappel, W‐J, Baglio, S, Ando, B, Sacco, V
2004
The role of M cells and the long QT syndrome in cardiac arrhythmias: simulation studies of reentrant excitations using a detailed electrophysiological model
Henry, Hervé, Rappel, Wouter-Jan
Noisy Fitzhugh-Nagumo model: From single elements to globally coupled networks
Acebrón, JA, Bulsara, AR, Rappel, W-J
Emergent oscillations in unidirectionally coupled overdamped bistable systems
Bulsara, Adi R, In, Visarath, Kho, Andy, Longhini, Patrick, Palacios, Antonio, Rappel, Wouter-Jan, Acebron, Juan, Baglio, Salvatore, Ando, Bruno
Cooperativity can reduce stochasticity in intracellular calcium dynamics
Wang, Kai, Rappel, Wouter-Jan, Levine, Herbert
2003
Probing a noisy oscillator system
Acebrón, JA, Rappel, W-J, Bulsara, AR
Injection locking near a stochastic bifurcation: the dc SQUID as a case study
Bulsara, AR, Acebrón, JA, Rappel, W-J, Hibbs, A, Kunstmanas, L, Krupka, M
Dynamics of globally coupled noisy excitable elements: The FitzHugh-Nagumo case
Acebrón, JA, Bulsara, AR, Rappel, W-J
Cooperative dynamics in a class of coupled two-dimensional oscillators
Acebrón, JA, Rappel, W-J, Bulsara, AR
Cooperative dynamics in a class of coupled two-dimensional oscillators
Torres, Juan, Rappel, W-J, Bulsara, AR
Computational approach for modeling intra-and extracellular dynamics
Kockelkoren, Julien, Levine, Herbert, Rappel, Wouter-Jan
2002
Noise-mediated cooperative behavior in a system of coupled DC SQUIDs
Acebron, Juan A, Bulsara, Adi R, Rappel, W-J
Establishing direction during chemotaxis in eukaryotic cells
Rappel, Wouter-Jan, Thomas, Peter J, Levine, Herbert, Loomis, William F
2001
Noise-mediated dynamics in a two-dimensional oscillator: Exact solutions and numerical results
Acebrón, JA, Bulsara, AR, Inchiosa, ME, Rappel, W-J
Modeling self-propelled deformable cell motion in the Dictyostelium mound; a status report
Rappel, Wouter-Jan, Levine, Herbert, Nicol, Alastair, Loomis, William F
Filament instability and rotational tissue anisotropy: a numerical study using detailed cardiac models
Rappel, Wouter-Jan
2000
Self-organization in systems of self-propelled particles
Levine, Herbert, Rappel, Wouter-Jan, Cohen, Inon
1999
Spatiotemporal control of wave instabilities in cardiac tissue
Rappel, Wouter-Jan, Fenton, Flavio, Karma, Alain
Self-organized vortex state in two-dimensional Dictyostelium dynamics
Rappel, Wouter-Jan, Nicol, Alastair, Sarkissian, Armand, Levine, Herbert, Loomis, William F
Phase-field model of dendritic sidebranching with thermal noise
Karma, Alain, Rappel, Wouter-Jan
Interdisciplinary Physics: Biological Physics, Quantum Information, etc-Self-organized Vortex State in Two-Dimensional Dictyostelium Dynamics
Rappel, Wouter-Jan, Nicol, Alastair, Sarkissian, Armand, Levine, Herbert, Loomis, William F
Cell-sorting in aggregates of Dictyostelium discoideum
Nicol, Alastair, Rappel, Wouter-Jan, Levine, Herbert, Loomis, William F
1998
Selection of doublet cellular patterns in directional solidification through spatially periodic perturbations
Losert, W, Stillman, DA, Cummins, HZ, Kopczyński, P, Rappel, W-J, Karma, A
Quantitative phase-field modeling of dendritic growth in two and three dimensions
Karma, Alain, Rappel, Wouter-Jan
PART B-Complex fluids, polymers, and granular materials-Selection of doublet cellular patterns in directional solidification through spatially periodic perturbations
Losert, W, Stillman, DA, Cummins, HZ, Kopczynski, P, Rappel, WJ, Karma, A
Model of banding in diffusive and convective regimes during directional solidification of peritectic systems
Karma, A, Rappel, W-J, Fuh, BC, Trivedi, R
1997
Phase-field simulation of three-dimensional dendrites: is microscopic solvability theory correct?
Karma, Alain, Rappel, Wouter-Jan
Collective chaos and noise in the globally coupled complex Ginzburg-Landau equation
Chabanol, Marie-Line, Hakim, Vincent, Rappel, Wouter-Jan
Cellular multiplets in directional solidification
Kopczyński, Przemek, Rappel, Wouter-Jan, Karma, Alain
1996
Phase-field modeling of crystal growth: New asymptotics and computational limits
Karma, Alain, Rappel, Wouter-Jan
Phase-field method for computationally efficient modeling of solidification with arbitrary interface kinetics
Karma, Alain, Rappel, Wouter-Jan
Numerical simulation of three-dimensional dendritic growth
Karma, Alain, Rappel, Wouter-Jan
Noise-induced coherence in neural networks
Rappel, Wouter-Jan, Karma, Alain
Critical role of crystalline anisotropy in the stability of cellular array structures in directional solidification
Kopczyński, Przemek, Rappel, Wouter-Jan, Karma, Alain
1995
Comment on “Spatial Subharmonics, Irrational Patterns, and Disorder in Eutectic Growth”
Karma, Alain, Rappel, Wouter-Jan
Coexisting pulses in a model for binary-mixture convection
Riecke, Hermann, Rappel, Wouter-Jan
1994
Stochastic resonance in an autonomous system with a nonuniform limit cycle
Rappel, Wouter-Jan, Strogatz, Steven H
Phase dynamics near a parity-breaking instability
Fourtune, Laurent, Rappel, Wouter-Jan, Rabaud, Marc
Noise-induced periodic behaviour in the globally coupled complex Ginzburg-Landau equation
Hakim, V, Rappel, W-J
1993
Cellular structures in step-flow growth
Misbah, Chaouqi, Rappel, Wouter-Jan
1992
The stability of cells in directional solidification
Rappel, Wouter-Jan, Brener, EA
Parity breaking in directional solidification: Numerics versus amplitude equations
Rappel, Wouter-Jan, Riecke, Hermann
Dynamics of the globally coupled complex Ginzburg-Landau equation
Hakim, Vincent, Rappel, Wouter-Jan
1991
The oscillatory instability in rapid solidification
Levine, Herbert, Rappel, Wouter-Jan
Resonant interactions and traveling-solidification cells
Levine, Herbert, Rappel, Wouter-Jan, Riecke, Hermann
1990
Patterns in Directional Solidification
Rappel, W-J
Numerical study for traveling waves in directional solidification
Levine, Herbert, Rappel, Wouter-Jan
1988
Exciton-polariton picture of the free-exciton lifetime in GaAs
Rappel, WJ, Feiner, LF, Schuurmans, MFH